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- Title
3D Real IR MR Findings in Acoustic Neuromas: Altered Perilymph Metabolism.
- Authors
Shi, Suming; Guo, Ping; Li, Wenquan; Wang, Wuqing
- Abstract
Objectives: This study aimed to investigate the perilymph metabolism by analyzing the 3D real IR MR findings in acoustic neuroma (AN) after intravenous administration of gadolinium (Gd). Methods: Eleven patients (6 men and 5 women) diagnosed with AN were included, and 3D real IR MRI was performed 4 hours after intravenous Gd injection. The signal intensity and details of inner ear, tumor, and internal auditory canal (IAC) by MRI were analyzed. Results: Four patients had tumors confined to the IAC, and 5 had tumors that extended to the cerebellopontine angle cistern. The signal intensity of the cochlea, vestibule, and IAC fundus was conspicuously enhanced in 3D real IR images than the control side. One patient had a tumor in the cochlea, in which the signal intensity of the semicircular canal and vestibule was increased. One patient had an intravestibular tumor in which the signal intensity of the semicircular canal was increased and the cochlea had endolymphatic hydrops in the affected ear. Conclusions: The synchronously increased signal intensity in the inner ear and IAC may indicate that IAC may serve as a channel for removal of the perilymph in the inner ear; the blockage by the tumor may have changed the hydrodynamics of the perilymph to cause a longer retention of Gd in the inner ear.
- Subjects
VESTIBULAR apparatus; THREE-dimensional imaging; RESEARCH funding; MAGNETIC resonance imaging; SIGNAL processing; MENIERE'S disease; INTRAVENOUS therapy; ACOUSTIC neuroma; EAR canal; INNER ear; PERILYMPH; CEREBELLUM; CONTRAST media; INTRAVENOUS injections; COCHLEA; SEMICIRCULAR canals; DRUG dosage; DRUG administration; DISEASE risk factors
- Publication
ENT: Ear, Nose & Throat Journal, 2024, Vol 103, Issue 3, pNP173
- ISSN
0145-5613
- Publication type
Article
- DOI
10.1177/01455613211047124