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- Title
Correlation Between the Presence of Antinuclear Antibodies and Recurrent Pregnancy Loss: A Mini Review.
- Authors
Liu, Ting; Guo, Xi; Liao, Ying; Liu, Yingyu; Zhu, Yuanfang; Chen, Xiaoyan
- Abstract
In the past decade, the incidence of recurrent pregnancy loss (RPL) has increased significantly, and immunological disorders have been considered as one of the possible causes contributing to RPL. The presence of antinuclear antibodies (ANAs) is regarded as a typical antibody of autoimmunity. However, the relationship between the presence of ANAs and RPL, the underlying mechanism, and the possible role of immunotherapy is still controversial. The aim of this mini review is to assess the association between ANAs and RPL and the effects of immunotherapy on pregnancy outcomes in women with positive ANAs and a history of RPL from the available data and to provide a relevant reference basis for clinical application in this group of women.
- Subjects
RECURRENT miscarriage; ANTINUCLEAR factors; PREGNANCY outcomes; CLINICAL medicine
- Publication
Frontiers in Endocrinology, 2022, Vol 13, p1
- ISSN
1664-2392
- Publication type
Article
- DOI
10.3389/fendo.2022.873286