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- Title
Cell viability and physicochemical effects of different concentrations of bismuth trioxide in a mineral trioxide aggregate cement.
- Authors
Padrón-Alvarado, Karla; García-Mendoza, Laura A.; Ramírez-Ortega, Juana P.; Rodríguez-Chavéz, Jacqueline A.; Moyaho-Bernal, María D. L. A.; Arreguín-Cano, Juan A.; Hoz-Rodríguez, Lia A.; Wintergerst, Ana; Arenas-Alatorre, Jesús A.; Flores-Ledesma, Abigailt
- Abstract
Purpose: To evaluate the effect of three concentrations of bismuth trioxide (Bi2O3) on the biological and physicochemical properties of an experimental mineral trioxide aggregate-type (MTA-type) cement at different time points. Methods: Three experimental groups with white Portland cement containing 15, 20, or 25 wt% of Bi2O3 were assessed. Cellular proliferation in human periodontal ligament fibroblasts was evaluated with an MTT assay. Radiopacity, dimensional stability, pH, and compressive strength were evaluated at different time points. Results: Bismuth trioxide induced cell proliferation in the Bi15 and Bi25 groups in a time-dependent manner; pH was similar in all groups. Compressive strength was associated with time and bismuth concentration. Bi25 had significantly contracted at day 7 and expanded at day 14 (ANOVA P < 0.05, post hoc Tukey test P < 0.05). Conclusion: A higher Bi2O3 concentration had a negative effect on the physical properties of the cement at all time points.
- Subjects
BISMUTH trioxide; MINERAL aggregates; CELL survival; PORTLAND cement; CEMENT
- Publication
Journal of Oral Science, 2023, Vol 65, Issue 1, p10
- ISSN
1343-4934
- Publication type
Article
- DOI
10.2334/josnusd.22-0139