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- Title
The global burden of major infectious complications following prostate biopsy.
- Authors
BENNETT, H. Y.; ROBERTS, M. J.; DOI, S. A. R.; GARDINER, R. A.
- Abstract
We present a systematic review providing estimates of the overall and regional burden of infectious complications following prostate biopsy. A directly standardized prevalence estimate was used because it reflects the burden of disease more explicitly. Complications included sepsis, hospitalization, bacteraemia, bacteriuria, and acute urinary retention after biopsy. There were 165 articles, comprising 162 577 patients, included in the final analysis. Our findings demonstrate that transrectal biopsy was associated with a higher burden of hospitalization (1·1% vs. 0·9%) and sepsis (0·8% vs. 0·1%) compared to transperineal biopsy, while acute urinary retention was more prevalent after transperineal than transrectal biopsy (4·2% vs. 0·9%). The differences were statistically non-significant because of large heterogeneity across countries. We also demonstrate and discuss regional variations in complication rates, with Asian studies reporting higher rates of sepsis and hospitalization.
- Subjects
PROSTATE biopsy; SEPSIS; BACTEREMIA; BACTERIURIA; RETENTION of urine; PROSTATE disease diagnosis; COMMUNICABLE disease epidemiology; BIOPSY; ECONOMIC aspects of diseases; META-analysis; WORLD health; SYSTEMATIC reviews; DISEASE prevalence
- Publication
Epidemiology & Infection, 2016, Vol 144, Issue 8, p1784
- ISSN
0950-2688
- Publication type
journal article
- DOI
10.1017/S0950268815002885