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- Title
RATES OF PLASMA PORPHRIN DISAPPEARANCE IN FLUORESCENT VS. RED INCANDESCENT LIGHT EXPOSURE.
- Authors
Poh-Fitzpatrick, Maureen B.; DeLeo, Vincent A.
- Abstract
The rates of porphyrin disappearance in plasma specimens were assessed during exposure to standard fluorescent room lighting. Protoporphyrin half-life in specimens from patients with erythropoietic protoporphyria appeared to be less than 30 min under these conditions. Uroporphyrin-coproporphyrin mixtures in plasmas of patients with porphyria cutanea tarda were more photostable, with half-lives measurable in terms of hours. All plasma porphyrins could be protected for several days from similar photodegradation by performing all blood drawing, processing, and assay procedures under ordinary red-incandescent illumination, and by storage in the dark.
- Subjects
FLUORESCENCE; INCANDESCENT electric lighting; PORPHYRINS; ERYTHROPOIETIC failure; FIRE assay; LIGHTING
- Publication
Journal of Investigative Dermatology, 1977, Vol 69, Issue 6, p510
- ISSN
0022-202X
- Publication type
Article
- DOI
10.1111/1523-1747.ep12687961