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- Title
Successful management of chromoblastomycosis utilizing conventional antifungal agents and imiquimod therapy.
- Authors
Zheng, Jinjin; Liu, Shougang; Xie, Zhenmou; Chen, Yangxia; Xi, Liyan; Liu, Hongfang; Liu, Yinghui
- Abstract
Chromoblastomycosis (CBM), a chronic fungal infection affecting the skin and subcutaneous tissues, is predominantly caused by dematiaceous fungi in tropical and subtropical areas. Characteristically, CBM presents as plaques and nodules, often leading to scarring post-healing. Besides traditional diagnostic methods such as fungal microscopy, culture, and histopathology, dermatoscopy and reflectance confocal microscopy can aid in diagnosis. The treatment of CBM is an extended and protracted process. Imiquimod, acting as an immune response modifier, boosts the host's immune response against CBM, and controls scar hyperplasia, thereby reducing the treatment duration. We present a case of CBM in Guangdong with characteristic reflectance confocal microscopy manifestations, effectively managed through a combination of itraconazole, terbinafine, and imiquimod, shedding light on novel strategies for managing this challenging condition.
- Subjects
GUANGDONG Sheng (China); IMMUNOMODULATORS; IMIQUIMOD; CONFOCAL microscopy; ITRACONAZOLE; MYCOSES; TREATMENT duration; ANTIFUNGAL agents
- Publication
Annals of Clinical Microbiology & Antimicrobials, 2024, Vol 23, Issue 1, p1
- ISSN
1476-0711
- Publication type
Article
- DOI
10.1186/s12941-024-00718-y