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- Title
Stopping Cancer Cells in Their Tracks….
- Authors
Kuwada, Scott K.
- Abstract
The article focuses on a study on the ability of the nuclear factor kappa B (NF-kB) inhibitors BAY 11-7082 or BAY 11-7085 to kill cancer cells during adhesion to the peritoneum. It offers an explanation of the process of metastasis by which cancer cells spread from primary tumors to secondary tissues, and is the leading cause of cancer deaths. It notes the activation of the transcription factor NF-kB when cancer cells in suspension adhere to a solid surface. The mechanism of action of the inhibitors is also discussed.
- Subjects
NF-kappa B; CANCER cells; CELL adhesion; PERITONEUM; METASTASIS; CANCER-related mortality; TRANSCRIPTION factors; BIOCHEMICAL mechanism of action
- Publication
Hawaii Medical Journal, 2009, Vol 68, Issue 10, p259
- ISSN
0017-8594
- Publication type
Article