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- Title
New trends in transient hyperthermia and liver preservation.
- Authors
Roselló‐Catafau, Joan
- Abstract
The investigations carried out by Charlotte von Horn and Thomas Minor [1] deal with the potential benefits of controlled hyperthermia for improving liver graft preservation against reperfusion insult. Certainly, an important indicator of liver graft conservation after THOR is the mitochondrial graft protection and the prevention of energy breakdown reflected by the increased (but not significant) ATP levels upon reperfusion conditions. In conclusion, using a "transient hyperthermic insult" during oxygenated perfusion in hypothermic and subnormothermic machine perfusion conditions may be useful to increase the graft protection against reperfusion injury.
- Subjects
FEVER; LIVER; HEAT shock proteins
- Publication
Transplant International, 2020, Vol 33, Issue 3, p270
- ISSN
0934-0874
- Publication type
Article
- DOI
10.1111/tri.13561