We found a match
Your institution may have access to this item. Find your institution then sign in to continue.
- Title
High HbA level was the most important factor associated with prevalence of diabetic retinopathy in Taiwanese type II diabetic patients with a fixed duration.
- Authors
Sheu, Shwu-Jiuan; Liu, Ni-Chun; Ger, Lu-Ping; Ho, Wan-Ling; Lin, Jiun-Yo; Chen, Shih-Chou; Horng, Yu-Harn; Lam, Hing-Chung
- Abstract
Background: To identify the prevalence and related risk factors for diabetic retinopathy (DR) in non-insulin dependent diabetes in Taiwan. Methods: A retrospective review of type II diabetic patients in the Diabetes Shared Care System database of our Hospital enrolled from 2002 to 2009. A retinopathy severity score was assigned according to fundus examination by indirect ophthalmoscopy or binocular biomicroscopy. Results: Data was collected on 901 subjects, 497 males and 404 females. Of these, 230 (25.53 %) had DR at enrolment. Compared with patients without DR, those with DR were more likely to be female ( p = 0.03) or have higher HbA ( p < 0.001), longer duration of diabetes ( p < 0.001), hypertension ( p < 0.001), higher systolic blood pressure ( p < 0.001), higher diastolic blood pressure ( p = 0.05), as well as impaired renal function ( p = 0.001). In subgroup analysis stratified by diabetes duration, HbA was the most consistent independent risk factor associated to the prevalence of DR. Higher systolic blood pressure and female sex were significantly independent risk factors only in patients with a duration of diabetes < 4 years. On the contrary, old onset age showed a protective effect against DR only in those with a disease duration > 8 years. Conclusions: High HbA level was the most important factor associated with prevalence of DR in Taiwanese type II DM patients with a fixed duration.
- Subjects
DIABETIC retinopathy; TYPE 2 diabetes; DISEASE prevalence; PROTOPHILIC solvents; OPHTHALMOSCOPY; SYSTOLIC blood pressure
- Publication
Graefe's Archive of Clinical & Experimental Ophthalmology, 2013, Vol 251, Issue 9, p2087
- ISSN
0721-832X
- Publication type
Article
- DOI
10.1007/s00417-013-2310-y