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The intracellular pharmacology of antiretroviral protease inhibitors.
Published in:
Journal of Antimicrobial Chemotherapy (JAC), 2004, v. 54, n. 6, p. 982, doi. 10.1093/jac/dkh487
By:
- J. Ford;
- S. H. Khoo;
- D. J. Back
Publication type:
Article
P-glycoprotein and MRP1 expression and reduced ritonavir and saquinavir accumulation in HIV-infected individuals.
Published in:
2002
By:
- Meaden, E. R.;
- Hoggard, P. G.;
- Newton, P.;
- Tjia, J. F.;
- Aldam, D.;
- Cornforth, D.;
- Lloyd, J.;
- Williams, I.;
- Back, D. J.;
- Khoo, S. H.
Publication type:
journal article
Antiretroviral drug concentrations in semen of HIV-infected men: differential penetration of indinavir, ritonavir and saquinavir.
Published in:
2001
By:
- Taylor, Stephen;
- Back, David J.;
- Drake, Susan M.;
- Workman, Judith;
- Reynolds, Helen;
- Gibbons, Sara E.;
- White, David J.;
- Pillay, Deenan;
- Taylor, S;
- Back, D J;
- Drake, S M;
- Workman, J;
- Reynolds, H;
- Gibbons, S E;
- White, D J;
- Pillay, D
Publication type:
journal article
The use of a darunavir/ritonavir once-daily regimen in two pregnant women.
Published in:
2010
By:
- Lambert, J. S.;
- Else, L. J.;
- Jackson, V.;
- Dickinson, L.;
- Back, D. J.;
- Brennan, M.;
- Weldridge, C.;
- Coulter-Smith, S.;
- Gibbons, S.;
- Khoo, S. H.
Publication type:
Abstract
Population pharmacokinetic modelling of oncedaily ritonavir-boosted darunavir in HIV-infected patients.
Published in:
2010
By:
- Dickinson, L.;
- Jackson, A. G. A.;
- Garvey, L. J.;
- Watson, V.;
- Khoo, S. H.;
- Winston, A.;
- Boffito, M.;
- Davies, G. R.;
- Back, D. J.
Publication type:
Abstract
Pharmacokinetics of plasma lopinavir/ritonavir following the administration of 400/100, 200/150, and 200/50 mg twice daily in HIV-negative volunteers.
Published in:
2010
By:
- Jackson, A. G. A.;
- Hill, A.;
- Else, L. J.;
- Back, D. J.;
- Morley, R.;
- Puls, R.;
- Amin, J.;
- Lin, E.;
- Boffito, M.
Publication type:
Abstract
SLCO3A1 expression is a major determinant of atazanavir PBMC penetration in HIV-infected patients.
Published in:
2010
By:
- Siccardi, M.;
- D'Avolio, A.;
- Baietto, L.;
- Simiele, M.;
- Bonora, S.;
- Back, D. J.;
- Di Perri, G.;
- Owen, A.
Publication type:
Abstract
Therapeutic drug monitoring (TDM) of atazanavir in pregnancy.
Published in:
2010
By:
- Else, L. J.;
- Jackson, V.;
- Brennan, M.;
- Breiden, J.;
- Weldridge, C.;
- Coulter-Smith, S.;
- Back, D. J.;
- Khoo, S. H.;
- Lambert, J.
Publication type:
Abstract
Evaluating pharmacist involvement in HIV outpatient clinics: can medication histories, drug interaction checks and adherence assessments add benefit?
Published in:
2010
By:
- Seden, K.;
- Back, D. J.;
- Khoo, S. H.
Publication type:
Abstract
O315. The pharmacokinetic and safety profile of raltegravir and ribavirin, when dosed separately and together, in healthy volunteers.
Published in:
2010
By:
- Ashby, J.;
- Garvey, L. J.;
- Erlwein, O. W.;
- Lamba, H.;
- Weston, R.;
- Legg, K.;
- McClure, M. O.;
- Dickinson, L.;
- D'Avolio, A.;
- Back, D. J.;
- Winston, A.
Publication type:
Abstract
O232. HIV therapy in an ageing population - the challenge of polypharmacy.
Published in:
2010
By:
- Back, D. J.
Publication type:
Abstract
Effect of azoles on the glucuronidation of zidovudine by human liver UDP-glucuronosyltransferase.
Published in:
1995
By:
- Asgari M;
- Back DJ;
- Asgari, M;
- Back, D J
Publication type:
Letter
Effect of Azoles on the Glucuronidation of Zidovudine by Human Liver UDP-Glucuronosyltransferase.
Published in:
Journal of Infectious Diseases, 1995, v. 172, n. 6, p. 1634, doi. 10.1093/infdis/172.6.1634
By:
- Asgari, M.;
- Back, D. J.
Publication type:
Article
The Relationships of ABCB1 3435C>T and CYP2B6 516G>T With High-Density Lipoprotein Cholesterol in HIV-Infected Patients Receiving Efavirenz.
Published in:
Clinical Pharmacology & Therapeutics, 2009, v. 86, n. 2, p. 204, doi. 10.1038/clpt.2009.78
By:
- Mahungu, T. W.;
- Nair, D.;
- Smith, C. J.;
- Egan, D.;
- Youle, M.;
- Johnson, M. A.;
- Khoo, S. H.;
- Back, D. J.;
- Owen, A.
Publication type:
Article
A Compartmental Pharmacokinetic Evaluation of Long-Acting Rilpivirine in HIV-Negative Volunteers for Pre-Exposure Prophylaxis.
Published in:
Clinical Pharmacology & Therapeutics, 2014, v. 96, n. 3, p. 314, doi. 10.1038/clpt.2014.118
By:
- Jackson, A G A;
- Else, L J;
- Mesquita, P M M;
- Egan, D;
- Back, D J;
- Karolia, Z;
- Ringner‐Nackter, L;
- Higgs, C J;
- Herold, B C;
- Gazzard, B G;
- Boffito, M
Publication type:
Article
Therapeutic drug monitoring of lopinavir/ritonavir in pregnancy.
Published in:
HIV Medicine, 2011, v. 12, n. 3, p. 166, doi. 10.1111/j.1468-1293.2010.00865.x
By:
- Lambert, J. S.;
- Else, L. J.;
- Jackson, V.;
- Breiden, J.;
- Gibbons, S.;
- Dickinson, L.;
- Back, D. J.;
- Brennan, M.;
- Connor, E. O.;
- Boyle, N.;
- Fleming, C.;
- Coulter-Smith, S.;
- Khoo, S. H.
Publication type:
Article
Cytochrome P450 2B6 516G→T is associated with plasma concentrations of nevirapine at both 200 mg twice daily and 400 mg once daily in an ethnically diverse population.
Published in:
HIV Medicine, 2009, v. 10, n. 5, p. 310, doi. 10.1111/j.1468-1293.2008.00689.x
By:
- Mahungu, T. W.;
- Smith, C. J.;
- Turner, F.;
- Egan, D.;
- Youle, M.;
- Johnson, M. A.;
- Khoo, S.;
- Back, D. J.;
- Owen, A.
Publication type:
Article
Current uses and future hopes for clinical pharmacology in the management of HIV infection.
Published in:
HIV Medicine, 2000, v. 1, p. 12, doi. 10.1046/j.1468-1293.2000.00001.x
By:
- Back, D. J.;
- Khoo, S. H.;
- Maher, B.;
- Gibbons, S. E.
Publication type:
Article
Effect of α<sub>1</sub>-acid glycoprotein on the intracellular accumulation of the HIV protease inhibitors saquinavir, ritonavir and indinavir in vitro.
Published in:
British Journal of Clinical Pharmacology, 2001, v. 51, n. 1, p. 99, doi. 10.1046/j.1365-2125.2001.01324.x
By:
- Jones, K.;
- Hoggard, P. G.;
- Khoo, S.;
- Maher, B.;
- Back, D. J.
Publication type:
Article
Differential inhibition of cytochrome P450 isoforms by the protease inhibitors, ritonavir, saquinavir and indinavir.
Published in:
British Journal of Clinical Pharmacology, 1997, v. 44, n. 2, p. 190, doi. 10.1046/j.1365-2125.1997.00644.x
By:
- Eagling, V. A.;
- Back, D. J.;
- Barry, M. G.
Publication type:
Article
Therapy with oral contraceptive steroids and antibiotics.
Published in:
1979
By:
- ORME, M. L'E.;
- BACK, D. J.;
- Orme, M L
Publication type:
journal article
Effect of etretinate on cyclosporin metabolism <em>in vitro</em>.
Published in:
British Journal of Dermatology, 1993, v. 128, n. 1, p. 42
By:
- Webber, I. R.;
- Back, D. J.
Publication type:
Article
Azoles, allylamines and drug metabolism.
Published in:
British Journal of Dermatology, 1992, v. 126, p. 14, doi. 10.1111/j.1365-2133.1992.tb00003.x
By:
- Back, D. J.;
- Tjia, J. F.;
- Abel, S. M.
Publication type:
Article
The in-vitro mucosal conjugation of ethinyloestradiol and the bioavailability of oral contraceptive steroids in patients with treated and untreated coeliac disease.
Published in:
Alimentary Pharmacology & Therapeutics, 1992, v. 6, n. 1, p. 79, doi. 10.1111/j.1365-2036.1992.tb00547.x
By:
- GRIMMER, S. F. M.;
- BACK, D. J.;
- ORME, M. L'E.;
- TJIA, J. F.;
- GILMORE, I. T.;
- ELLIS, A.
Publication type:
Article
Review: first-pass metabolism by the gastrointestinal mucosa.
Published in:
Alimentary Pharmacology & Therapeutics, 1987, v. 1, n. 5, p. 339, doi. 10.1111/j.1365-2036.1987.tb00634.x
By:
- BACK, D. J.;
- ROGERS, S. M.
Publication type:
Article
The impact of cytokines on the expression of drug transporters, cytochrome P450 enzymes and chemokine receptors in human PBMC.
Published in:
2009
By:
- Liptrott, N. J.;
- Penny, M.;
- Bray, P. G.;
- Sathish, J.;
- Khoo, S. H.;
- Back, D. J.;
- Owen, A.
Publication type:
journal article
Cultured CD4T cells and primary human lymphocytes express hOATPs: intracellular accumulation of saquinavir and lopinavir.
Published in:
2008
By:
- Janneh, O.;
- Hartkoorn, R. C.;
- Jones, E.;
- Owen, A.;
- Ward, S. A.;
- Davey, R.;
- Back, D. J.;
- Khoo, S. H.
Publication type:
journal article
Comparison of the induction profile for drug disposition proteins by typical nuclear receptor activators in human hepatic and intestinal cells.
Published in:
2008
By:
- Martin, P.;
- Riley, R.;
- Back, D. J.;
- Owen, A.
Publication type:
journal article
Pharmacokinetics of mefloquine alone or in combination with artesunate.
Published in:
Bulletin of the World Health Organization, 1994, v. 72, n. 1, p. 83
By:
- Karbwang, J.;
- Na Bangchang, K.;
- Thanavibul, A.;
- Back, D. J.;
- Bunnag, D.;
- Harinasuta, T.
Publication type:
Article
The impact of pharmacogenetics on HIV therapy.
Published in:
International Journal of STD & AIDS, 2009, v. 20, n. 3, p. 145, doi. 10.1258/ijsa.2008.008369
By:
- Mahungu, T. W.;
- Johnson, M. A.;
- Owen, A.;
- Back, D. J.
Publication type:
Article
Prevalence and type of drug-drug interactions involving ART in patients attending a specialist HIV outpatient clinic in Kampala, Uganda.
Published in:
2015
By:
- Seden, K.;
- Merry, C.;
- Hewson, R.;
- Siccardi, M.;
- Lamorde, M.;
- Byakika-Kibwika, P.;
- Laker, E.;
- Parkes-Ratanshi, R.;
- Back, D. J.;
- Khoo, S. H.
Publication type:
journal article
Interactions between tenofovir and nevirapine in CD4+ T cells and monocyte-derived macrophages restrict their intracellular accumulation.
Published in:
Journal of Antimicrobial Chemotherapy (JAC), 2013, v. 68, n. 11, p. 2545, doi. 10.1093/jac/dkt225
By:
- Liptrott, N. J.;
- Curley, P.;
- Moss, D.;
- Back, D. J.;
- Khoo, S. H.;
- Owen, A.
Publication type:
Article

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