We found a match
Your institution may have access to this item. Find your institution then sign in to continue.
- Title
Relationship between Cytotoxicity and Surface Oxidation of Artificial Black Carbon.
- Authors
Le, Yen Thi-Hoang; Youn, Jong-Sang; Moon, Hi-Gyu; Chen, Xin-Yu; Kim, Dong-Im; Cho, Hyun-Wook; Lee, Kyu-Hong; Jeon, Ki-Joon
- Abstract
The lacking of laboratory black carbon (BC) samples have long challenged the corresponding toxicological research; furthermore, the toxicity tests of engineered carbon nanoparticles were unable to reflect atmospheric BC. As a simplified approach, we have synthesized artificial BC (aBC) for the purpose of representing atmospheric BC. Surface chemical properties of aBC were controlled by thermal treatment, without transforming its physical characteristics; thus, we were able to examine the toxicological effects on A549 human lung cells arising from aBC with varying oxidation surface properties. X-ray photoelectron spectroscopy, as well as Raman and Fourier transform infrared spectroscopy, verified the presence of increased amounts of oxygenated functional groups on the surface of thermally-treated aBC, indicating aBC oxidization at elevated temperatures; aBC with increased oxygen functional group content displayed increased toxicity to A549 cells, specifically by decreasing cell viability to 45% and elevating reactive oxygen species levels up to 294% for samples treated at 800 °C.
- Subjects
SOOT; CARBON-black; FOURIER transform infrared spectroscopy; REACTIVE oxygen species; X-ray photoelectron spectroscopy; CHEMICAL properties
- Publication
Nanomaterials (2079-4991), 2021, Vol 11, Issue 6, p1455
- ISSN
2079-4991
- Publication type
Article
- DOI
10.3390/nano11061455