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- Title
The genetics of vertebrate myogenesis.
- Authors
Bryson-Richardson, Robert J.; Currie, Peter D.
- Abstract
The molecular, genetic and cellular bases for skeletal muscle growth and regeneration have been recently documented in a number of vertebrate species. These studies highlight the role of transient subcompartments of the early somite as a source of distinct waves of myogenic precursors. Individual myogenic progenitor populations undergo a complex series of cell rearrangements and specification events in different regions of the body, all of which are controlled by distinct gene regulatory networks. Collectively, these studies have opened a window into the morphogenetic and molecular bases of the different phases of vertebrate myogenesis, from embryo to adult.
- Subjects
VERTEBRATES; GENETICS; MYOGENESIS; EMBRYOLOGY; SOMITE
- Publication
Nature Reviews Genetics, 2008, Vol 9, Issue 8, p632
- ISSN
1471-0056
- Publication type
Article
- DOI
10.1038/nrg2369