We found a match
Your institution may have access to this item. Find your institution then sign in to continue.
- Title
Diagnostic Value of Lung-To-Liver Signal Intensity Ratio as An Indicator of Fetal Lung Maturity in Third-Trimester Pregnancy Using Magnetic Resonance Imaging.
- Authors
Taqi, Fatima Hasan; Kadhim, Mohammed Abd
- Abstract
Background: fetal Magnetic resonance imaging (MRI) is effective and non-invasive, more accurate method for examining fetal lung development and predicting fetal respiratory outcomes. Aims of the study: to study fetal lung-to-liver signal intensity ratio (LLSIR) using MR imaging T2-weighted images to indicate fetal lung maturity and predict neonatal respiratory outcome in third-trimester pregnancy and to establish an ideal LLSIR cutoff value Patients and Methods: a prospective study was conducted on 40 fetuses from 39 pregnant women who delivered within 24 hours of an MRI scan during the period from January 2021 and January 2022 in AL-Imamain Al-Kadhimain Medical City/Baghdad/Iraq. LLSIR was evaluated using Half-Fourier acquisition single-shot turbo spinecho (HASTE) MRI. An analysis of the receiver operating characteristic (ROC) curve was utilized to figure out the ideal cut-off value for the LLSIR to predict respiratory prognosis after delivery was determined. Results: The gestational ages ranged from 28.1 to 40 weeks (mean 34.8 weeks). It was revealed that there was a correlation between magnetic resonance LLSIR and gestational age (p-value 0.001). The non-respiratory distress syndrome group had higher LLSIR compared with the respiratory distress syndrome group (2.81±0.32vs. 2.19±0.18, p-value 0.001). Compared to the preterm group, the term group exhibited a greater LLSIR. (2.87±0.34 vs 2.34±0.29, p-value 0.001). ROC curve analysis showed LLSIR at a cut-off value of LLSIR ≤ 2.32 and AUC=0.977, revealing high sensitivity (100%) and high specificity (88.9%). Conclusions: The third-trimester LLSIR, as determined by T2-weighed images MRI, might be utilized as a prognostic marker for the neonatal respiratory prognosis if there is a strong correlation between these two parameters. 2.32 is the recommended cut-off number for forecasting newborn respiratory survival.
- Subjects
BAGHDAD (Iraq); IRAQ; MAGNETIC resonance imaging; FETAL MRI; RESPIRATORY distress syndrome; RECEIVER operating characteristic curves; PREGNANCY outcomes
- Publication
Kerbala Jorunal of Medicine, 2022, Vol 15, Issue 2, p2571
- ISSN
1990-5483
- Publication type
Article