We found a match
Your institution may have access to this item. Find your institution then sign in to continue.
- Title
Sustained Resolution of Multifocal Low-Grade Dysplasia in Ulcerative Colitis.
- Authors
Canakis, Andrew; Dellatore, Peter; Josephson, Matthew; Canakis, Justin; Alruwaii, Zainab; Lazarev, Mark; Brant, Steven R.
- Abstract
In inflammatory bowel disease, prolonged disease duration, pancolitis, histological inflammation, and subsequent dysplasia are associated with an increased risk for colorectal cancer. Recommendations regarding treatment of low-grade dysplasia (LGD) indicate an individualized approach between colectomy and surveillance. Wepresent a unique case of a patient with ulcerative colitis who had multifocal LGD on 2 consecutive colonoscopies. However, after 10 years and 16 surveillance colonoscopies, she had no further evidence of dysplasia. This appears to be the first case of proven, permanently resolved multifocal LGD in inflammatory bowel disease that challenges our understanding of the natural history of LGD.
- Subjects
COLON physiology; ULCERATIVE colitis diagnosis; RECTUM tumors; COLON tumors; COLECTOMY; COLONOSCOPY; INFLAMMATORY bowel diseases; PRECANCEROUS conditions; PUBLIC health surveillance; ULCERATIVE colitis; DISEASE management; TUMOR risk factors; CANCER risk factors
- Publication
ACG Case Reports Journal, 2019, Vol 6, Issue 9, p1
- ISSN
2326-3253
- Publication type
Article
- DOI
10.14309/crj.0000000000000178