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- Title
Increased risk of depression in patients with lupus erythematosus.
- Authors
Hesselvig, J.H.; Egeberg, A.; Kofoed, K.; Gislason, G.; Dreyer, L.
- Abstract
Summary: Lupus is a chronic autoimmune disease, meaning the body's immune system works against the body instead of protecting it. Systemic lupus may not only involve the skin but also internal organs such as lungs, heart, and kidneys, and is potentially a fatal disease, whereas cutaneous lupus is mainly restricted to the skin. It affects women more often than men and symptoms usually first appear when patients are aged in their 30s. This study, from Denmark, investigated if patients with lupus (cutaneous or systemic) have increased risk of depression. By using the unique Danish nationwide registers, the authors found that patients diagnosed with systemic or cutaneous lupus both had a 2‐fold increased risk of a subsequent diagnosis of depression compared with the general population in Denmark. Likewise, the risk of severe depression was increased for patients with cutaneous or systemic lupus. On the other hand, the risk of self‐harm and death from suicide were not significantly increased in patients with lupus. Surprisingly, the risk of depression is of similar magnitude for patients with systemic lupus, a potentially fatal disease, as for patients with cutaneous lupus. This indicates that the involvement of the skin has the same important impact as the systemic disease on the patients' mental health. It is relevant that both dermatologists and patients know about this significant increase in risk of depression. Linked Article: Hesselvig et al. Br J Dermatol 2018; 179:1095–1101
- Subjects
MENTAL depression risk factors; LUPUS erythematosus; SYSTEMIC lupus erythematosus
- Publication
British Journal of Dermatology, 2018, Vol 179, Issue 5, pe205
- ISSN
0007-0963
- Publication type
Abstract
- DOI
10.1111/bjd.17216