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- Title
Extraction Process and Quality Standard of Danshen Jianxin Capsules.
- Authors
Chengtong LIU; Xinying MO; Silu HE; Donglian CHEN; Guilin YANG; Hongsheng TAN; Peng LIANG; Haisheng ZENG
- Abstract
Objectives] This study was conducted to establish the quality standard of Danshen Jianxin Capsules. [Methods] Orthogonal design was adopted to optimize the water extraction process by taking the amount of water added, extraction time and extraction times as factors, and the content of tanshinone I as the index. Salviae Miltiorrhizae, Notoginseng Radix Et Rhizoma and Radix Astragali in the capsules were qualitatively identified by TLC, and the content of tanshinone I in the capsules was determined by HPLC. [Results] The best water extraction process included the steps of adding 12 times of water each time, extracting the materials twice, for 1 h each time. In TLC identification, the test samples showed spots of the same color at the positions corresponding to tanshinone II A, ginsenoside Rgl, notoginsenoside R1 and astragaloside IV reference samples. [Conclusions] Danshen Jianxin Capsules was prepared by the water extraction method, which is characterized by high efficiency and being suitable for mass production. The quality control method is reliable, fast and accurate, which can effectively control the quality of the product.
- Subjects
SALVIA miltiorrhiza; QUALITY standards; QUALITY control; MASS production; GINSENOSIDES
- Publication
Medicinal Plant, 2023, Vol 14, Issue 1, p25
- ISSN
2152-3924
- Publication type
Article
- DOI
10.19600/j.cnki.issn2152-3924.2023.01.005