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- Title
Malignant peripheral nerve sheath tumour of penis.
- Authors
Kaur, J.; Madan, R.; Singh, L.; Sharma, D. N.; Julka, P. K.; Rath, G. K.; Roy, S.
- Abstract
Malignant peripheral nerve sheath tumour ( MPNST) is a rare variety of soft tissue sarcoma that originates from Schwann cells or pluripotent cells of neural crest origin. They have historically been difficult tumours to diagnose and treat. Surgery is the mainstay of treatment with a goal to achieve negative margins. Despite aggressive surgery and adjuvant therapy, the prognosis of patients with MPNST remains poor. MPNST arising from penis is a very rare entity; thus, it presents a diagnostic and therapeutic challenge. We present a case of penile MPNST in a 38-year-old man in the absence of neurofibromatosis treated with surgery followed by post-operative radiotherapy to a dose of 60 Gray in 30 fractions and adjuvant chemotherapy with ifosfamide and adriamycin.
- Subjects
PERIPHERAL nervous system; PENIS; GENITALIA; MALE reproductive organs; PENIS sheaths
- Publication
Andrologia, 2015, Vol 47, Issue 3, p333
- ISSN
0303-4569
- Publication type
Article
- DOI
10.1111/and.12267