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- Title
Alteration of synergistic immune response in gut–liver axis of white crucian carp (Carassius cuvieri) after gut infection with Aeromonas hydrophila.
- Authors
Wang, Fei; Qin, Zi‐Le; Luo, Wei‐Sheng; Xiong, Ning‐Xia; Huang, Ming‐Zhu; Ou, Jie; Luo, Sheng‐Wei; Liu, Shao‐Jun
- Abstract
Aeromonas hydrophila can pose a great threat to the survival of farmed fish. In current study, we investigated the pathological characteristics and immune response in gut–liver axis of white crucian carp (WCC) upon gut infection. WCC anally intubated with A. hydrophila exerted a tissue deformation in damaged midgut with elevated levels of goblet cells along with a significant decrease in tight junction proteins and villi length‐to‐width ratios. In addition, immune‐related gene expressions and antioxidant properties increased dramatically in gut–liver axis of WCC following gut infection with A. hydrophila. These results highlighted the immune modulation and redox alteration in gut–liver axis of WCC in response to gut infection.
- Subjects
AEROMONAS hydrophila; CRUCIAN carp; IMMUNE response; IMMUNOREGULATION; TIGHT junctions; GENE expression
- Publication
Journal of Fish Diseases, 2023, Vol 46, Issue 9, p917
- ISSN
0140-7775
- Publication type
Article
- DOI
10.1111/jfd.13799