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- Title
Uso de biomarcadores na sepse pediátrica: revisão de literatura.
- Authors
Lanziotti, Vanessa Soares; Póvoa, Pedro; Soares, Márcio; Lapa e Silva, José Roberto; Barbosa, Arnaldo Prata; Figueira Salluh, Jorge Ibrain
- Abstract
Despite advances in recent years, sepsis is still a leading cause of hospitalization and mortality in infants and children. The presence of biomarkers during the response to an infectious insult makes it possible to use such biomarkers in screening, diagnosis, prognosis (risk stratification), monitoring of therapeutic response, and rational use of antibiotics (for example, the determination of adequate treatment length). Studies of biomarkers in sepsis in children are still relatively scarce. This review addresses the use of biomarkers in sepsis in pediatric patients with emphasis on C-reactive protein, procalcitonin, interleukins 6, 8, and 18, human neutrophil gelatinase, and proadrenomedullin. Assessment of these biomarkers may be useful in the management of pediatric sepsis.
- Publication
Revista Brasileira de Terapia Intensiva, 2016, Vol 28, Issue 4, p472
- ISSN
0103-507X
- Publication type
Article
- DOI
10.5935/0103-507X.20160080