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- Title
Immunoglobulin Deficiency and Idiotype Expression in Children Developing Haemophilus influenzae Type b Disease After Vaccination With Conjugate Vaccine.
- Authors
Holmes, Sandra J.; Lucas, Alexander H.; Osterholm, Michael T.; Froeschle, James E.; Granoff, Dan M.
- Abstract
Investigates host factors in children who developed Haemophilus influenzae type b (Hib) disease despite conjugate vaccination. Presence of subnormal serum immunoglobulin concentrations; Anticapsular antibody responses to Hib disease; Expression of the Hib idiotype 1; Relative risk of a subnormal serum concentration.
- Subjects
HAEMOPHILUS diseases; VACCINATION of children; IMMUNOGLOBULINS
- Publication
JAMA: Journal of the American Medical Association, 1991, Vol 266, Issue 14, p1960
- ISSN
0098-7484
- Publication type
Article
- DOI
10.1001/jama.1991.03470140072027