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- Title
Multivariate considerations in the evalution of periodontal clinical trials.
- Authors
Zimmerman, Stuart O.
- Abstract
This article informs that nearly every adult suffers from periodontal disease to some degree. Because of this universal distribution, some measure of severity or intensity of the disease is necessary in order to have any sensitivity in the evaluation of clinical trials. Amongst certain variables, particularly those concerned with oral hygiene, differences in anatomic site may make inhomogeneous what was before a homogeneous variable, particularly in regard to evaluation of therapy. A regimen effective in removing interproximal plaque, such as flossing, would have little, if any, effect on facial plaque.
- Subjects
MEDICAL experimentation on humans; CLINICAL medicine; CLINICAL trials; SANITATION; HYGIENE; MEDICAL research
- Publication
Journal of Periodontal Research, 1974, Vol 9, p111
- ISSN
0022-3484
- Publication type
Article
- DOI
10.1111/j.1600-0765.1974.tb01772.x