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Analysis by two-dimensional Blue Native/SDS-PAGE of membrane protein alterations in rat soleus muscle after hindlimb unloading.
- Published in:
- 2010
- By:
- Publication type:
- journal article
Ion Channel Involvement in Tumor Drug Resistance.
- Published in:
- Journal of Personalized Medicine, 2022, v. 12, n. 2, p. N.PAG, doi. 10.3390/jpm12020210
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- Publication type:
- Article
Chaperone activity of niflumic acid on ClC-1 chloride channel mutants causing myotonia congenita.
- Published in:
- Frontiers in Pharmacology, 2022, v. 13, p. 1, doi. 10.3389/fphar.2022.958196
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- Publication type:
- Article
Ion Channels in Multiple Myeloma: Pathogenic Role and Therapeutic Perspectives.
- Published in:
- International Journal of Molecular Sciences, 2022, v. 23, n. 13, p. 7302, doi. 10.3390/ijms23137302
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- Publication type:
- Article
Disuse of rat muscle in vivo reduces protein kinase C activity controlling the sarcolemma chloride conductance.
- Published in:
- Journal of Physiology, 2007, v. 584, n. 3, p. 983, doi. 10.1113/jphysiol.2007.141358
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- Publication type:
- Article
Different flecainide sensitivity of hNa<sub>v</sub> 1.4 channels and myotonic mutants explained by state-dependent block.
- Published in:
- Journal of Physiology, 2004, v. 554, n. 2, p. 321, doi. 10.1113/jphysiol.2003.046995
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- Publication type:
- Article
A large cohort of myotonia congenita probands: novel mutations and a high-frequency mutation region in exons 4 and 5 of the CLCN1 gene.
- Published in:
- Journal of Human Genetics, 2013, v. 58, n. 9, p. 581, doi. 10.1038/jhg.2013.58
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- Publication type:
- Article
Growth hormone secretagogues modulate the electrical and contractile properties of rat skeletal muscle through a ghrelin-specific receptor.
- Published in:
- British Journal of Pharmacology, 2003, v. 139, n. 3, p. 575, doi. 10.1038/sj.bjp.0705284
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- Publication type:
- Article
Increased rigidity of the chiral centre of tocainide favours stereoselectivity and use-dependent block of skeletal muscle Na<sup>+</sup> channels enhancing the antimyotonic activity in vivo.
- Published in:
- British Journal of Pharmacology, 2001, v. 134, n. 7, p. 1523, doi. 10.1038/sj.bjp.0704366
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- Publication type:
- Article
Increased hindrance on the chiral carbon atom of mexiletine enhances the block of rat skeletal muscle Na+ channels in a model of myotonia induced by ATX.
- Published in:
- 1999
- By:
- Publication type:
- journal article
Corrigendum: Bioisosteric Modification of To042: Synthesis and Evaluation of Promising Use‐Dependent Inhibitors of Voltage‐Gated Sodium Channels.
- Published in:
- ChemMedChem, 2022, v. 17, n. 7, p. 1, doi. 10.1002/cmdc.202200131
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- Publication type:
- Article
Bioisosteric Modification of To042: Synthesis and Evaluation of Promising Use‐Dependent Inhibitors of Voltage‐Gated Sodium Channels.
- Published in:
- ChemMedChem, 2021, v. 16, n. 23, p. 3588, doi. 10.1002/cmdc.202100496
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- Publication type:
- Article
Synthesis and Evaluation of Voltage‐Gated Sodium Channel Blocking Pyrroline Derivatives Endowed with Both Antiarrhythmic and Antioxidant Activities.
- Published in:
- ChemMedChem, 2021, v. 16, n. 3, p. 578, doi. 10.1002/cmdc.202000692
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- Publication type:
- Article
In vivo longitudinal study of rodent skeletal muscle atrophy using ultrasonography.
- Published in:
- Scientific Reports, 2016, p. 20061, doi. 10.1038/srep20061
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- Publication type:
- Article
Effects of Nandrolone in the Counteraction of Skeletal Muscle Atrophy in a Mouse Model of Muscle Disuse: Molecular Biology and Functional Evaluation.
- Published in:
- PLoS ONE, 2015, v. 10, n. 6, p. 1, doi. 10.1371/journal.pone.0129686
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- Publication type:
- Article
Effects of Pleiotrophin Overexpression on Mouse Skeletal Muscles in Normal Loading and in Actual and Simulated Microgravity.
- Published in:
- PLoS ONE, 2013, v. 8, n. 8, p. 1, doi. 10.1371/journal.pone.0072028
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- Publication type:
- Article
Paracrine Effects of IGF-1 Overexpression on the Functional Decline Due to Skeletal Muscle Disuse: Molecular and Functional Evaluation in Hindlimb Unloaded MLC/mIgf-1 Transgenic Mice.
- Published in:
- PLoS ONE, 2013, v. 8, n. 6, p. 1, doi. 10.1371/journal.pone.0065167
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- Publication type:
- Article
Adaptation of Mouse Skeletal Muscle to Long-Term Microgravity in the MDS Mission.
- Published in:
- PLoS ONE, 2012, v. 7, n. 3, p. 1, doi. 10.1371/journal.pone.0033232
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- Publication type:
- Article
Buprenorphine may be effective for treatment of paramyotonia congenita.
- Published in:
- 2021
- By:
- Publication type:
- journal article
Potential benefits of taurine in the prevention of skeletal muscle impairment induced by disuse in the hindlimb-unloaded rat.
- Published in:
- Amino Acids, 2012, v. 43, n. 1, p. 431, doi. 10.1007/s00726-011-1099-4
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- Publication type:
- Article
How to obtain an integrated picture of the molecular networks involved in adaptation to microgravity in different biological systems?
- Published in:
- NPJ Microgravity, 2024, v. 10, n. 1, p. 1, doi. 10.1038/s41526-024-00395-3
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- Publication type:
- Article
Immunoglobulin Replacement Therapy: Insights into Multiple Myeloma Management.
- Published in:
- Cancers, 2024, v. 16, n. 18, p. 3190, doi. 10.3390/cancers16183190
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- Publication type:
- Article
Anti-Angiogenic Activity of Drugs in Multiple Myeloma.
- Published in:
- Cancers, 2023, v. 15, n. 7, p. 1990, doi. 10.3390/cancers15071990
- By:
- Publication type:
- Article
Immersive and Non-Immersive Virtual Reality for Pain and Anxiety Management in Pediatric Patients with Hematological or Solid Cancer: A Systematic Review.
- Published in:
- Cancers, 2023, v. 15, n. 3, p. 985, doi. 10.3390/cancers15030985
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- Publication type:
- Article
The Landscape of lncRNAs in Multiple Myeloma: Implications in the "Hallmarks of Cancer", Clinical Perspectives and Therapeutic Opportunities.
- Published in:
- Cancers, 2022, v. 14, n. 8, p. 1963, doi. 10.3390/cancers14081963
- By:
- Publication type:
- Article
Emerging Roles for Ion Channels in Ovarian Cancer: Pathomechanisms and Pharmacological Treatment.
- Published in:
- Cancers, 2021, v. 13, n. 4, p. 668, doi. 10.3390/cancers13040668
- By:
- Publication type:
- Article
Hydroxylated Analogs of Mexiletine as Tools for Structural-Requirements Investigation of the Sodium Channel Blocking Activity.
- Published in:
- Archiv der Pharmazie, 2010, v. 343, n. 6, p. 325, doi. 10.1002/ardp.200900218
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- Publication type:
- Article
Skeletal muscle ClC-1 chloride channels in health and diseases.
- Published in:
- Pflügers Archiv: European Journal of Physiology, 2020, v. 472, n. 7, p. 961, doi. 10.1007/s00424-020-02376-3
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- Publication type:
- Article
Protein kinase C theta (PKCθ) modulates the ClC-1 chloride channel activity and skeletal muscle phenotype: a biophysical and gene expression study in mouse models lacking the PKCθ.
- Published in:
- Pflügers Archiv: European Journal of Physiology, 2014, v. 466, n. 12, p. 2215, doi. 10.1007/s00424-014-1495-1
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- Publication type:
- Article
Inhibition of skeletal muscle sodium currents by mexiletine analogues: specific hydrophobic interactions rather than lipophilia per se account for drug therapeutic profile.
- Published in:
- Naunyn-Schmiedeberg's Archives of Pharmacology, 2003, v. 367, n. 3, p. 318, doi. 10.1007/s00210-002-0669-0
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- Publication type:
- Article
ClC-1 chloride channels: state-of-the-art research and future challenges.
- Published in:
- Frontiers in Cellular Neuroscience, 2015, v. 9, p. 1, doi. 10.3389/fncel.2015.00156
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- Publication type:
- Article
Clinical, Molecular, and Functional Characterization of CLCN1 Mutations in Three Families with Recessive Myotonia Congenita.
- Published in:
- NeuroMolecular Medicine, 2015, v. 17, n. 3, p. 285, doi. 10.1007/s12017-015-8356-8
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- Publication type:
- Article
Change of chloride ion channel conductance is an early event of slow‐to‐fast fibre type transition during unloading‐induced muscle disuse.
- Published in:
- Brain: A Journal of Neurology, 2002, v. 125, n. 7, p. 1510, doi. 10.1093/brain/awf162
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- Publication type:
- Article
Multidisciplinary study of a new ClC-1 mutation causing myotonia congenita: a paradigm to understand and treat ion channelopathies.
- Published in:
- FASEB Journal, 2016, v. 30, n. 10, p. 3285, doi. 10.1096/fj.201500079R
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- Publication type:
- Article
A c.1775C > T Point Mutation of Sodium Channel Alfa Subunit Gene (SCN4A) in a Three-Generation Sardinian Family with Sodium Channel Myotonia.
- Published in:
- Journal of Neuromuscular Diseases, 2024, v. 11, n. 3, p. 725, doi. 10.3233/JND-230134
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- Publication type:
- Article
Targeted Therapies for Skeletal Muscle Ion Channelopathies: Systematic Review and Steps Towards Precision Medicine.
- Published in:
- Journal of Neuromuscular Diseases, 2021, v. 8, n. 3, p. 357, doi. 10.3233/JND-200582
- By:
- Publication type:
- Article
Therapeutic Approaches to Genetic Ion Channelopathies and Perspectives in Drug Discovery.
- Published in:
- Frontiers in Pharmacology, 2016, p. 1, doi. 10.3389/fphar.2016.00121
- By:
- Publication type:
- Article
Editorial: Recent Advances in Voltage-Gated Sodium Channels, their Pharmacology and Related Diseases.
- Published in:
- 2016
- By:
- Publication type:
- Editorial
Inhibition of voltage-gated sodium channels by sumatriptan bioisosteres.
- Published in:
- Frontiers in Pharmacology, 2015, p. 1, doi. 10.3389/fphar.2015.00155
- By:
- Publication type:
- Article
Correction to: A guide to writing systematic reviews of rare disease treatments to generate FAIRcompliant datasets: building a Treatabolome.
- Published in:
- 2021
- By:
- Publication type:
- corrected article
A guide to writing systematic reviews of rare disease treatments to generate FAIR-compliant datasets: building a Treatabolome.
- Published in:
- 2020
- By:
- Publication type:
- journal article
Decrease in resting calcium and calcium entry associated with slow-to-fast transition in unloaded rat soleus muscle.
- Published in:
- FASEB Journal, 2003, v. 17, n. 13, p. 1916
- By:
- Publication type:
- Article
Effect of microgravity on gene expression in mouse brain.
- Published in:
- Experimental Brain Research, 2008, v. 191, n. 3, p. 289, doi. 10.1007/s00221-008-1523-5
- By:
- Publication type:
- Article
Dramatic improvement of myotonia permanens with flecainide: a two-case report of a possible bench-to-bedside pharmacogenetics strategy.
- Published in:
- 2013
- By:
- Publication type:
- Letter
Editorial: New Insights in Skeletal Muscle Channelopathies - A Rapidly Expanding Field.
- Published in:
- 2020
- By:
- Publication type:
- Editorial
Pathomechanisms of a CLCN1 Mutation Found in a Russian Family Suffering From Becker's Myotonia.
- Published in:
- Frontiers in Neurology, 2020, v. 11, p. N.PAG, doi. 10.3389/fneur.2020.01019
- By:
- Publication type:
- Article
Long-Term Safety and Usefulness of Mexiletine in a Large Cohort of Patients Affected by Non-dystrophic Myotonias.
- Published in:
- Frontiers in Neurology, 2020, v. 11, p. 1, doi. 10.3389/fneur.2020.00300
- By:
- Publication type:
- Article
Missense and Non-Missense Lamin A/C Gene Mutations Are Similarly Associated with Major Arrhythmic Cardiac Events: A 20-Year Single-Centre Experience.
- Published in:
- Biomedicines, 2024, v. 12, n. 6, p. 1293, doi. 10.3390/biomedicines12061293
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- Publication type:
- Article
Uptake-Dependent and -Independent Effects of Fibroblasts-Derived Extracellular Vesicles on Bone Marrow Endothelial Cells from Patients with Multiple Myeloma: Therapeutic and Clinical Implications.
- Published in:
- Biomedicines, 2023, v. 11, n. 5, p. 1400, doi. 10.3390/biomedicines11051400
- By:
- Publication type:
- Article
Musculoskeletal Features without Ataxia Associated with a Novel de novo Mutation in KCNA1 Impairing the Voltage Sensitivity of Kv1.1 Channel.
- Published in:
- Biomedicines, 2021, v. 9, n. 1, p. 75, doi. 10.3390/biomedicines9010075
- By:
- Publication type:
- Article