We found a match
Your institution may have access to this item. Find your institution then sign in to continue.
- Title
Analysis of patchclamp recordings: model-free multiscale methods and software.
- Authors
Pein, Florian; Eltzner, Benjamin; Munk, Axel
- Abstract
Analysis of patchclamp recordings is often a challenging issue. We give practical guidance how such recordings can be analyzed using the model-free multiscale idealization methodology JSMURF, JULES, and HILDE. We provide an operational manual how to use the accompanying software available as an R-package and as a graphical user interface. This includes selection of the right approach and tuning of parameters. We also discuss advantages and disadvantages of model-free approaches in comparison to hidden Markov model approaches and explain how they complement each other.
- Subjects
HIDDEN Markov models; COMPUTER software; MARKOV processes
- Publication
European Biophysics Journal, 2021, Vol 50, Issue 2, p187
- ISSN
0175-7571
- Publication type
Article
- DOI
10.1007/s00249-021-01506-8