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- Title
A Clone with 5,17 and 18 Monosomies as Stemline in a Patient with De novo Acute Myeloid Leukemia.
- Authors
Zare-Abdollahi, Davood; Movafagh, Abolfazl; Safari, Shamsi; Omrani, MirDavood
- Abstract
In brief, we present a case of acute myeloid leukemia (AML) with 5, 17 and 18 monosomies as stemline clonal abnormality in hiscytoge-netic analysis. To the best of our knowledge, this is the first report of such a chromosomal abnormality as a clonal aberration in AML with MO French-American-British (FAB) type. It seems that this monosomal karyotype imposed adverse prognosis on this patient and could be related to the rapid and malignant course of the disease as seen.
- Subjects
CHROMOSOME abnormalities; ACUTE myeloid leukemia diagnosis; BONE marrow examination; CYTOGENETICS; KARYOTYPES; ACUTE myeloid leukemia; DIAGNOSIS
- Publication
Archives of Iranian Medicine (AIM), 2016, Vol 19, Issue 5, p379
- ISSN
1029-2977
- Publication type
Article