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- Title
Effect of Growth Hormone Replacement on BMD in Adult-Onset Growth Hormone Deficiency.
- Authors
Snyder, Peter J.; Biller, Beverly M. K.; Zagar, Anthony; Jackson, Ivor; Arafah, Baha M.; Nippoldt, Todd B.; Cook, David M.; Mooradian, Arshag D.; Kwan, Anita; Scism-Bacon, Jamie; Chipman, John J.; Hartman, Mark L.
- Abstract
The article cites a study that performed a randomized, placebo-controlled trial to determine whether growth hormone (GH) replacement would increase lumbar spine bone mineral density (BMD) in a combined group of men and women with adult-onset GH deficiency (GHD). Results showed that BMD of the lumbar spine in the entire group has increased above baseline in the GH-treated subjects. Based on the results, it has been concluded that GH replacement significantly increased spine BMD in men by 3.8%.
- Subjects
SOMATOTROPIN; PITUITARY dwarfism; PITUITARY diseases; LUMBAR vertebrae; SOMATOMEDIN; DISEASES in older people; BONE density; BONE densitometry; DISEASE risk factors
- Publication
Journal of Bone & Mineral Research, 2007, Vol 22, Issue 5, p762
- ISSN
0884-0431
- Publication type
Article
- DOI
10.1359/JBMR.070205