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- Title
In vitro investigation of anticholinesterase activity of four biochemical pesticides: spinosad, pyrethrum, neem bark extract and veratrine.
- Authors
BUCUR, Madalina Petruta; BUCUR, Bogdan; MARTY, Jean-Louis; RADU, Gabriel-Lucian
- Abstract
The anticholinesterase activity of four biochemical pesticides: spinosad, pyrethrum, neem bark extract and veratrine was tested against one acetylcholinesterase extracted from Electrophorus electricus and two from Drosophila melanogaster. Pyrethrum, neem bark extract, and veratrine induced a dose-related inhibition of a variable type. Electric eel cholinesterase was inhibited uncompetitively by neem bark extract, the inhibition of the wilde-type fruit fly enzyme by pyrethrum was competitive, and the other enzyme-biochemical pesticide inhibitions were non-competitive. The sensitivity of each enzyme toward biochemical pesticides was variable.
- Subjects
IN vitro studies; SPINOSAD; PYRETHRUM (Plant); NEEM; VERATRINE; CHOLINESTERASE inhibitors; PESTICIDE analysis
- Publication
Journal of Pesticide Science, 2014, Vol 39, Issue 1, p48
- ISSN
1348-589X
- Publication type
Article
- DOI
10.1584/jpestics.D13-062