We found a match
Your institution may have access to this item. Find your institution then sign in to continue.
- Title
Factors associated with hospitalization for seasonal influenza in Morocco.
- Authors
Ezzine, Hind; Regragui, Zakia; Cherkaoui, Imad; Naciri, Mariam; Filali-Maltouf, Abdelkarim; Rguig, Ahmed; Triki, Soumia; Elkholy, Amgad; Bimouhen, Abderrahman; Falaki, Fatima; Ihazmad, Hassan; Benamar, Touria; Oumzil, Hicham; Youbi, Mohammed
- Abstract
Background: Morocco is actively working towards expanding its influenza vaccine policy to cover high-risk groups, as recommended by the World Health Organization (WHO). Aims: We assessed the risk factors for influenza-associated hospitalization for severe acute respiratory infections (SARI) that occurred during the last 5 seasons. Methods: We conducted a retrospective, analytical study among patients recruited in the ambulatory and hospital sites of the influenza sentinel surveillance system in Morocco between 2014 and 2019. Using multiple logistic regression, we compared the characteristics of influenza-positive patients with SARI to those with influenza-like illness (ILI) to identify factors associated with severe disease. Results: We included 1323 positive influenza patients with either SARI (41.7%) or ILI diagnosis (58.3%). A(H1N1)pdm09, A(H3N2) and influenza B, respectively, contributed 49.2%, 29.5% and 20.6% of the cases. The main risk factors considered in the bivariate analysis were found in the multivariate analysis to be significantly associated with influenza-related hospitalization (SARI): age < 2 years (aOR = 7.08, P < 0.001); age ≥ 65 years (aOR = 3.59, P < 0.001); diabetes (aOR = 1.98, P = 0.017); obesity (aOR = 2.94, P = 0.034); asthma or chronic respiratory disease (aOR = 4.99, P < 0.001); chronic renal failure (aOR = 4.74, P = 0.005); pregnancy (aOR = 7.49, P < 0.001); and the A(H1N1)pdm09 subtype (aOR = 1.82, P < 0.001). Conclusion: This study provides epidemiological evidence for the expected benefit of an influenza vaccination strategy for high-risk groups as recommended by the WHO.
- Subjects
MOROCCO; PUBLIC health surveillance; H1N1 influenza; STATISTICS; WORLD Health Organization; MULTIPLE regression analysis; MULTIVARIATE analysis; RETROSPECTIVE studies; ACQUISITION of data; RISK assessment; COMPARATIVE studies; SEASONAL influenza; HOSPITAL care; MEDICAL records; RESEARCH funding; INFLUENZA B virus; DESCRIPTIVE statistics; ODDS ratio; SARS disease; INFLUENZA A virus, H3N2 subtype; DISEASE risk factors; DISEASE complications
- Publication
Eastern Mediterranean Health Journal, 2023, Vol 29, Issue 6, p441
- ISSN
1020-3397
- Publication type
Article
- DOI
10.26719/emhj.23.072