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- Title
Optimal dietary macronutrient distribution in China (ODMDC): a randomised controlled-feeding trial protocol.
- Authors
Yi Wan; Fenglei Wang; Jihong Yuan; Duo Li; Wan, Yi; Wang, Fenglei; Yuan, Jihong; Li, Duo
- Abstract
<bold>Background and Objectives: </bold>Findings from observational studies in China show that increased dietary fat consumption might be a contributor to the developing obesity epidemic. However, some cohort studies suggest that carbohydrate intake, especially from white rice, is a risk factor for obesity, type 2 diabetes and coronary heart disease in China. Our study aims to determine whether the traditional lower-fat, higher-carbohydrate Chinese or the Western higher-fat, lower-carbohydrate dietary pattern is more effective for weight control and the related cardiometabolic profiles increasingly found among contemporary Chinese.<bold>Methods and Study Design: </bold>The Optimal Dietary Macronutrient Distribution in China (ODMDC) trial is a 6-month, multi-centre, three-arm controlled feeding study. Based on the macronutrient transition in the past 30 years in China, three isoenergetic diets with a spectrum of fat and carbohydrate intake, but same protein contents, have been formulated. Percentages of fat, carbohydrate, and protein energy are one of 20, 66 and 14%; 30, 56 and 14%; 40, 46 and 14%, respectively. Participants will be provided with all their food and most beverages for 6 months.<bold>Results: </bold>The study population is planned to be 300 healthy non-obese adults aged 18 to 35 years. The primary outcome is body weight and the secondary variables are waist circumference and cardiometabolic risk factors.<bold>Conclusions: </bold>The ODMDC trial will have implications for nutrition policy in regard to weight control and related cardiometabolic disturbances among otherwise healthy non-obese Chinese.
- Subjects
CHINA; EPIDEMICS; EPIDEMIOLOGY; OBESITY; CARBOHYDRATES; BIOMOLECULES; CARDIOVASCULAR disease prevention; METABOLIC disorders; BODY weight; REGULATION of body weight; CARBOHYDRATE content of food; FAT content of food; MEDICAL cooperation; RESEARCH protocols; NUTRITIONAL requirements; DIETARY proteins; REDUCING diets; RESEARCH; WAIST circumference; PREVENTION
- Publication
Asia Pacific Journal of Clinical Nutrition, 2017, Vol 26, Issue 5, p972
- ISSN
0964-7058
- Publication type
journal article
- DOI
10.6133/apjcn.072017.06