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- Title
Reflexes Inhibited by a Prepulse: Intensity of Startle Stimulus and Prepulse Across Onset Intervals.
- Authors
Ryoji Nishiyama; Hiroyuki Isoy
- Abstract
Prepulse inhibition refers to the inhibition of the startle reflexes by a weak stimulus (prepulse) that precedes a strong startle stimulus (pulse). Previous findings suggest that prepulse intensity affects prepulse inhibition amplitude and that prepulse inhibition amplitudes vary across onset intervals between the prepulse and pulse. However, evidence regarding the effect of startle stimulus intensity is still inconclusive, especially due to variations between prepulse inhibition scores calculated by using percentage-type and difference-type formulas. Moreover, the combined effect of startle stimulus and prepulse intensities across onset intervals remains poorly understood. The present study investigated the combined effect as well as the influence of startle response amplitudes on the formulae used for the calculation. The results suggest that startle stimulus intensity could potentially affect results of percentage-type formulae for calculating prepulse inhibition over a wide range of lead intervals. Furthermore, the results demonstrated that a combination of strong startle stimulus intensities and weak prepulse intensities could not induce prepulse inhibition at long onset intervals (1000ms and 2000ms).
- Subjects
NOISE &; psychology; ANALYSIS of variance; ANIMAL experimentation; PROBABILITY theory; RATS; REFLEXES; STATISTICS; T-test (Statistics); DATA analysis; DATA analysis software; DESCRIPTIVE statistics; ACOUSTIC stimulation
- Publication
Perceptual & Motor Skills, 2016, Vol 123, Issue 1, p153
- ISSN
0031-5125
- Publication type
Article
- DOI
10.1177/0031512516659718