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- Title
Phlorotannins as Radical Scavengers from the Extract of Sargassum ringgoldianum.
- Authors
Nakai, Masaaki; Kageyama, Norihiko; Nakahara, Koichi; Miki, Wataru
- Abstract
To screen algal phlorotannins with antioxidative activities, 50% ethanol extracts of 25 Japanese marine algae were evaluated. Scavenging activity against superoxide anion radicals was frequently found with a high content of total phenolic compounds. Among these, the extract from the brown seaweed, Sargassum ringgoldianum, showed the strongest scavenging activity. The active fraction contained a mixture of high molecular weight polyphenols, phlorotannins that were found to be polymerized bifuhalol, as analyzed by matrix-assisted laser desorption/ionization time-of-flight mass spectrometry (MALDI-TOF MS). The scavenging activity of the fraction against superoxide anion radicals was estimated to be 1.0 μg/ml (IC50), which were approximately five times stronger than that of catechin.
- Subjects
MARINE algae; SARGASSUM; PHENOLS; MOLECULAR weights; TIME-of-flight mass spectrometry; CATECHIN
- Publication
Marine Biotechnology, 2006, Vol 8, Issue 4, p409
- ISSN
1436-2228
- Publication type
Article
- DOI
10.1007/s10126-005-6168-9