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- Title
Within-Household Transmission and Bacterial Diversity of Staphylococcus pseudintermedius.
- Authors
Wegener, Alice; Duim, Birgitta; van der Graaf-van Bloois, Linda; Zomer, Aldert L.; Visser, Caroline E.; Spaninks, Mirlin; Timmerman, Arjen J.; Wagenaar, Jaap A.; Broens, Els M.
- Abstract
Staphylococcus pseudintermedius can be transmitted between dogs and their owners and can cause opportunistic infections in humans. Whole genome sequencing was applied to identify the relatedness between isolates from human infections and isolates from dogs in the same households. Genome SNP diversity and distribution of plasmids and antimicrobial resistance genes identified related and unrelated isolates in both households. Our study shows that within-host bacterial diversity is present in S. pseudintermedius, demonstrating that multiple isolates from each host should preferably be sequenced to study transmission dynamics.
- Subjects
BACTERIAL diversity; WHOLE genome sequencing; STAPHYLOCOCCUS; OPPORTUNISTIC infections; INFECTIOUS disease transmission; PLASMIDS
- Publication
Pathogens, 2022, Vol 11, Issue 8, p850
- ISSN
2076-0817
- Publication type
Article
- DOI
10.3390/pathogens11080850