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- Title
Safety and efficacy of intra-articular infiltration of purified autologous adipose tissue for osteoarthritis treatment: a pre-post study.
- Authors
López, Félix
- Abstract
Keywords: Osteoarthritis; Knee; Cartilage; Regenerative medicine; Adipose tissue; Mesenchymal stem cells; Lipocell EN Osteoarthritis Knee Cartilage Regenerative medicine Adipose tissue Mesenchymal stem cells Lipocell 1 5 5 09/28/22 20220927 NES 220927 Introduction Osteoarthritis (OA) is a degenerative cartilage disease that affects joints, causing pain and disability. Therefore, the aim of this study was to analyze the clinical follow-up of patients with knee OA, including those with grade IV OA, treated with intra-articular injections of purified autologous micro-fragmented adipose tissue obtained with the medical device Lipocell. Materials and methods Study design and patients This was an analysis of patients with symptomatic knee OA who underwent an intra-articular injection of purified adipose tissue between March 2018 and July 2019 at two centers in Madrid: Maestranza Medical Center and Beata María Ana Hospital. Abbreviations AD-MSCs Adipose-derived mesenchymal stem cells BMI Body mass index MSCs Mesenchymal stem cells OA Osteoarthritis PRP Platelet-rich-plasma VAS Visual analogue scale WOMAC Western ontario and mcmaster universities osteoarthritis index Publisher's Note Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations.
- Subjects
INTRA-articular injections; ADIPOSE tissues; KNEE pain; BODY mass index; OSTEOARTHRITIS; ABDOMINAL adipose tissue; MESENCHYMAL stem cells
- Publication
Journal of Experimental Orthopaedics, 2022, Vol 9, Issue 1, p1
- ISSN
2197-1153
- Publication type
Article
- DOI
10.1186/s40634-022-00534-3