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- Title
Synthesis of 7-[2-(Dimethylamino)vinyl]pyrazolo[1,5-a]pyrimidine-6-carbonitriles and Their Heterocyclizations with N1 Synthons.
- Authors
Polikarchuk, V. A.; Derkachev, M. S.; Shikhaliev, Kh. S.
- Abstract
The use of new 7-methylazolo[1,5-a]pyrimidine-6-carbonitriles for the construction of heterocyclic systems annulated at the pyrimidine ring has been demonstrated. Cascade cyclizations are carried out via the intermediate dimethylaminovinyl derivatives. The specific features of the cascade reactions with ammonia or aliphatic amines as N1 synthons, depending on the reaction conditions, are demonstrated.
- Subjects
ALIPHATIC amines; PYRIMIDINES; ANNULATION; RING formation (Chemistry); AMMONIA
- Publication
Russian Journal of Organic Chemistry, 2024, Vol 60, Issue 5, p852
- ISSN
1070-4280
- Publication type
Article
- DOI
10.1134/S1070428024050087