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- Title
Time course of a new spectral electroencephalographic marker of sleep homeostasis.
- Authors
Putilov, Arcady
- Abstract
Background and objective: As compared to preceding wakefulness, stage 1 sleep is characterized by elevated slow-wave activity (SWA) that is regarded as the most popular electroencephalographic (EEG) indicator of sleep debt. However, some other indicators did not suggest such elevation until stage 2 sleep. In this paper, a more direct indicator of the signature left by sleep debt in the sleep EEG spectrum named 'spectral sleep debt component score' (SDS) was introduced, and its changes throughout three stages of non-rapid eye movement (NREM) sleep were studied. Materials and methods: Records of 9-h night sleep episodes followed by nine 20-min naps (14 females), as well as twelve 20-min naps after either a 7-h sleep or sleep deprivation (18 males) were used for calculation of spectra consisting of 16 single-Hz log-transformed EEG power density values (range 1 to 16 Hz). The 16 weights for calculating SDS from each such spectrum were obtained by subtracting spectra with lower sleep debt from spectra with higher sleep debt (i. e., the spectra for the last vs. first 100 min of night sleep and for the last vs. first 20-min nap). Results: As expected, SWA started its significant rise already during stage 1 sleep. By contrast, a rise in SDS was delayed until the boundary with stage 2, thus confirming the findings using other indicators of sleep debt. Conclusion: It seems that stage 1 is a transient sleep sub-state that only prepares for, rather than participates in, the sleep debt payment process. Such a conclusion has practical relevance for evaluation of abnormalities of sleep architecture.
- Subjects
SLEEP-wake cycle; ELECTROENCEPHALOGRAPHY; BIOMARKERS; HOMEOSTASIS; SLOW wave sleep
- Publication
Somnologie, 2016, Vol 20, Issue 2, p134
- ISSN
1432-9123
- Publication type
Article
- DOI
10.1007/s11818-016-0051-y