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- Title
Dexamethasone improves vascular hyporeactivity induced by LPS in vivo by modulating ATP-sensitive potassium channels activity.
- Authors
d'Emmanuele di Villa Bianca, R.; Lippolis, L.; Autore, G.; Popolo, A.; Marzocco, S.; Sorrentino, L.; Pinto, A.; Sorrentino, R.
- Abstract
Studies the effect of dexamethasone on vascular hyporeactivity in lipopolysaccharide-induced endotoxemia in rats. Modulation of adenosine triphosphate-sensitive potassium channels activity; Effect on glybenclamide-induced hypertension; Impact of simultaneous administration of dexamethasone and lipopolysaccharide on hyporeactivity to phenyephrine.
- Subjects
SEPTIC shock; ENDOTOXINS; POTASSIUM channels; GLUCOCORTICOIDS
- Publication
British Journal of Pharmacology, 2003, Vol 140, Issue 1, p91
- ISSN
0007-1188
- Publication type
Article
- DOI
10.1038/sj.bjp.0705406