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- Title
Coordinate-Based Meta-Analysis of fMRI Studies with R.
- Authors
Stocco, Andrea
- Abstract
This paper outlines how to conduct a simple meta-analysis of neuroimaging foci of activation in R. In particular, the first part of this paper reviews the nature of fMRI data, and presents a brief overview of the existing packages that can be used to analyze fMRI data in R. The second part illustrates how to handle fMRI data by showing how to visualize the results of different neuroimaging studies in a so-called orthographic view, where the spatial distribution of the foci of activation from different fMRI studies can be inspected visually. Functional MRI (fMRI) is one of the most important and powerful tools of neuroscientific research. Although not as commonly used for fMRI analysis as some specific applications such as SPM (Friston et al., 2006), AFNI (Cox and Hyde, 1997), or FSL (Smith et al., 2004), R does provide several packages that can be employed in neuroimaging research. These packages deal with a variety of topics, ranging from reading and manipulating fMRI datasets, to implementing sophisticated statistical models. The goal of this paper is to provide a brief introduction to fMRI analysis, and the various R packages that can be used to carry it out. As an example, it will show how to use simple R commands to read fMRI images and plot results from previous studies, which can then be visually compared. This is a special form of meta-analysis, and a common way to compare results from the existing literature.
- Subjects
FUNCTIONAL magnetic resonance imaging; MAGNETIC resonance imaging; MEDICAL research evaluation; META-analysis; QUANTITATIVE research
- Publication
R Journal, 2014, Vol 6, Issue 2, p5
- ISSN
2073-4859
- Publication type
Article
- DOI
10.32614/RJ-2014-020