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- Title
Vestibular Rehabilitation with Intratympanic Drug Therapy in Meniere's Disease.
- Authors
Ayub, Zeeshan; Ashfaq, Ahmed Hasan; Khan, Amir Ali; Butt, Kamran Ashfaq Ahmed
- Abstract
Objective: To evaluate vertigo control and auditory rescue in patients with Meniere's disease treated with intratympanic Gentamicin and Dexamethasone. Study Design: Randomized Control Trial (Clinical Trials. gov Identifier: NCT05355610). Place and Duration of Study: ENT Departments CMH Quetta and Benazir Bhutto Hospital Rawalpindi Pakistan from Apr 2020 to Mar 2022. Methodology: Ninety-three cases of unilateral Meniere's disease meeting the inclusion criteria were treated with intratympanic Gentamicin and Dexamethasone. Pre and post-treatment vertigo was assessed on Vestibular Deficit Index. Speech discrimination scores for auditory impact were also recorded pre and post-treatment. Results: In the Ninety-three treated cases, there was a statistically significant improvement in the Vestibular Deficit Index (with a p-value of 0.001). Although all patients had a reduced speech discrimination score, it was not statistically significant (p value=0.08). Conclusion: Control of vestibular symptoms can be achieved with intratympanic Gentamicin, and at the same time, the auditory system can be rescued with Dexamethasone.
- Subjects
PAKISTAN; QUETTA (Pakistan); MENIERE'S disease; DRUG therapy; SUBSTANCE abuse treatment; SPEECH perception; AUDITORY pathways; VERTIGO
- Publication
Pakistan Armed Forces Medical Journal, 2022, Vol 72, Issue 4, p1444
- ISSN
0030-9648
- Publication type
Article
- DOI
10.51253/pafmj.v72i4.8696