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- Title
Development and validation of the Vitiligo Extent Score for a Target Area (VESTA) to assess the treatment response of a target lesion.
- Authors
Bae, Jung Min; Oh, Sang Ho; Kang, Hee Young; Ryoo, Young Wook; Lan, Cheng‐Che E.; Xiang, Lei‐Hong; Kim, Ki‐Ho; Suzuki, Tamio; Katayama, Ichiro; Lee, Seung‐Chul
- Abstract
Since localized treatment for vitiligo is as essential as systemic treatment, a reliable instrument for target evaluation is needed besides those for whole body evaluation. We developed the Vitiligo Extent Score for a Target Area (VESTA) using reference images of both marginal and perifollicular repigmentation to measure the repigmentation rate (%) in a target lesion. In the validation study, a total of 65 dermatologists in 10 institutes evaluated 17 pairs of vitiligo images (pre‐ and post‐treatment) using both a rough estimate and the VESTA. The VESTA (concordance correlation coefficient: 0.949, 95% confidence interval [CI] 0.942–0.955) was significantly more accurate than the rough estimate (0.896, 95% CI: 0.883–0.908). It was also associated with better inter‐rater reliability over the rough estimate, albeit not significant. The VESTA can afford intuitive, convenient, and reliable assessment of the treatment response in a target area, and would be useful in clinical practice as well as retrospective studies.
- Subjects
VITILIGO; PIGMENTATION disorders; TISSUE wounds; RETROSPECTIVE studies; CONFIDENCE intervals
- Publication
Pigment Cell & Melanoma Research, 2019, Vol 32, Issue 2, p315
- ISSN
1755-1471
- Publication type
Article
- DOI
10.1111/pcmr.12730