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- Title
Prediction of Packed Cell Volume after Whole Blood Transfusion in Small Ruminants and South American Camelids: 80 Cases (2006-2016).
- Authors
Luethy, D.; Stefanovski, D.; Salber, R.; Sweeney, R.W.
- Abstract
Background Calculation of desired whole blood transfusion volume relies on an estimate of an animal's circulating blood volume, generally accepted to be 0.08 L/kg or 8% of the animal's body weight in kilograms. Objective To use packed cell volume before and after whole blood transfusion to evaluate the accuracy of a commonly used equation to predict packed cell volume after transfusion in small ruminants and South American camelids; to determine the nature and frequency of adverse transfusion reactions in small ruminants and camelids after whole blood transfusion. Animals Fifty-eight small ruminants and 22 alpacas that received whole blood transfusions for anemia. Methods Retrospective case series; medical record review for small ruminants and camelids that received whole blood transfusions during hospitalization. Results Mean volume of distribution of blood as a fraction of body weight in sheep (0.075 L/kg, 7.5% BW) and goats (0.076 L/kg, 7.6% BW) differed significantly ( P < 0.01) from alpacas (0.103 L/kg, 10.3% BW). Mild transfusion reactions were noted in 16% of transfusions. Conclusions and Clinical Relevance The generally accepted value of 8% for circulating blood volume (volume of distribution of blood) is adequate for calculation of transfusion volumes; however, use of the species-specific circulating blood volume can improve calculation of transfusion volume to predict and achieve desired packed cell volume. The incidence of transfusion reactions in small ruminants and camelids is low.
- Subjects
CELL size; BLOOD transfusion reaction; ANEMIA treatment; SHEEP physiology; PHYSIOLOGY; GOATS; CAMELIDAE
- Publication
Journal of Veterinary Internal Medicine, 2017, Vol 31, Issue 6, p1900
- ISSN
0891-6640
- Publication type
Article
- DOI
10.1111/jvim.14844