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- Title
Polymerase Chain Reaction of Plasma and Bronchoalveolar Lavage Fluid for Diagnosing Invasive Aspergillosis.
- Authors
White, P Lewis; Donnelly, J Peter
- Abstract
An editorial focuses on two studies regarding the diagnosis of invasive aspergillosis (IA) using polymerase chain reaction (PCR) on plasma and bronchoalveolar lavage (BAL) fluid. It discusses the findings of these studies, emphasizing the improved accuracy of PCR in plasma compared to traditional tests like galactomannan. It also explores the challenges and questions raised by the studies, particularly in the context of the current definitions and classification criteria for IA.
- Subjects
BODY fluid analysis; ANTIFUNGAL agents; POLYSACCHARIDES; BRONCHOALVEOLAR lavage; DNA; BLOOD plasma; DRUG resistance; PULMONARY aspergillosis; GENETIC markers; ENZYME-linked immunosorbent assay; POLYMERASE chain reaction; EXTRACELLULAR space; COMPUTED tomography; BIOLOGICAL assay; COLLECTION &; preservation of biological specimens; NUCLEIC acids; BLOOD
- Publication
Clinical Infectious Diseases, 2023, Vol 77, Issue 9, p1291
- ISSN
1058-4838
- Publication type
Editorial
- DOI
10.1093/cid/ciad421