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- Title
Position statement on the diagnosis and management of non-alcoholic fatty liver disease.
- Authors
Alswat, Khalid A.; Fallatah, Hind I.; Al-Judaibi, Bandar; Elsiesy, Hussien A.; Al-Hamoudi, Waleed K.; Qutub, Adel N.; Alturaify, Naif; Al-Osaimi, Abdullah
- Abstract
Non-alcoholic fatty liver disease (NAFLD) is a major national and international health burden. It is one of the most common liver diseases worldwide and the most common cause of abnormal liver enzymes in many developed countries. Non-alcoholic fatty liver disease is also known as an important cause of cryptogenic cirrhosis and second leading cause for liver transplantation. It is commonly associated with metabolic syndrome. Nonalcoholic steatohepatitis (NASH) is the progressive phenotype of NAFLD. In spite of promising performance of non-invasive tools, liver biopsy remains the gold standard test for NASH diagnosis. Over decades, many drugs have been investigated in phase 2 and 3; however, no approved therapy to date. Despite the alarming global rates of NAFLD, there are no local community-based studies on the prevalence of NAFLD or local practice guidelines on its management; this expert review aims to fill this gap.
- Subjects
FATTY liver; LIVER disease diagnosis; LIVER disease treatment; LIVER enzymes; LIVER biopsy; DISEASE management
- Publication
Saudi Medical Journal, 2019, Vol 40, Issue 6, p531
- ISSN
0379-5284
- Publication type
Article
- DOI
10.15537/smj.2019.6.23980