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- Title
Effectiveness of lifestyle intervention on prevention/management of antipsychotic-induced weight gain among persons with severe mental illness: A systematic review and meta-analysis.
- Authors
Mohanty, Krutideepa; Gandhi, Sailaxmi; Krishna Prasad, Muliyala; John, Annie P; Bhaskarapillai, Binukumar; Malo, Palash; Thirthalli, Jagadisha
- Abstract
Individualized lifestyle interventions using motivational interviewing (MI) approach are recommended for persons with severe mental illness (SMI) for effective weight management. The aim of this meta-analysis was to assess the effectiveness of various lifestyle interventions that addressed obesity among persons with SMI. Twelve RCTs were assessed by individual reviewers using revised cochrane risk-of-bias tool (RoB 2). The standardized mean difference (SMD) was calculated with a 95% CI. The age of participants was between 18 and 70 years. Waist circumference showed an SMD of −0.09 (−0.22, 0.03), weight −0.03 (−0.10, 0.15) and BMI −0.07 (−0.07, 0.22). The findings in this meta-analysis revealed that though lifestyle interventions were statistically insignificant in reducing antipsychotic induced weight gain among persons with SMI, they show changes in intervention group. Psychosocial management along with lifestyle interventions, and MI are effective in the management of antipsychotic induced weight gain.
- Subjects
MEDICAL information storage &; retrieval systems; BEHAVIOR modification; BODY mass index; CINAHL database; ANTIPSYCHOTIC agents; SEVERITY of illness index; TREATMENT effectiveness; META-analysis; DESCRIPTIVE statistics; SYSTEMATIC reviews; MEDLINE; WAIST circumference; HEALTH behavior; ONLINE information services; CONFIDENCE intervals; WEIGHT gain; PSYCHOLOGY information storage &; retrieval systems; PHARMACODYNAMICS; EVALUATION
- Publication
Journal of Health Psychology, 2024, Vol 29, Issue 7, p690
- ISSN
1359-1053
- Publication type
Article
- DOI
10.1177/13591053241227384