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- Title
`Continuous muscle fibre activity' in six dogs with episodic myokymia, stiffness and collapse.
- Authors
Van Ham, L.; Bhatti, S.; Polis, I.; Fatzer, R.; Braund, K.; Thoonen, H.
- Abstract
Continuous muscle fibre activity was observed in a crossbred dog, a Yorkshire terrier, a border collie and three Jack Russell terriers. The clinical signs consisted of episodes of generalised myokymia which developed into muscle stiffness and delayed muscle relaxation and generally led to the dogs collapsing into lateral recumbency. These episodes were preceded by intense facial rubbing in three of the dogs, and were associated with severe hyperthermia in five of them. All three Jack Russell terriers showed continuous ataxia. The dogs had above normal activities of aspartate aminotransferase, alanine aminotransferase and creatine kinase, but their cerebrospinal fluid was normal. Myokymic discharges were observed by electromyography in two of the dogs. Two of them were treated with membrane-stabilising agents, with variable results.
- Subjects
MUSCLE contraction; DOG diseases; DOG breeds; ASPARTATE aminotransferase; CREATINE kinase; CEREBROSPINAL fluid
- Publication
Veterinary Record: Journal of the British Veterinary Association, 2004, Vol 155, Issue 24, p769
- ISSN
0042-4900
- Publication type
Article