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- Title
Squamous Cell Carcinoma of the Buccal Mucosa: A 40‐Year Review.
- Authors
DeConde, Adam; Palla, Beth; Chhetri, Dinesh; Miller, Mia E.; St. John, Maie; Elashoff, David
- Abstract
Objective: Evaluate the treatment results of buccal squamous cell carcinoma at a single institution during a 40‐year period. Method: A retrospective review was performed by examining the records and reviewing the pathology of 48 patients with buccal squamous cell carcinoma treated at UCLA Medical Center from 1970 to 2009. Forty‐eight patients were identified that received first‐time surgical therapy for squamous cell carcinoma of the buccal mucosa and had adequate follow‐up. Results: Treatment entailed surgery alone in 18 out of 48 patients (37.5%) and surgery followed by radiation therapy in 30 out of 48 patients (62.5%). Composite resection of the tumor was performed in 17 out of 48 patients (35.4%) and ipsilateral neck dissections were performed in 37 out of 48 patients (77.1%). One‐year observed actuarial disease‐free survival rates were 60%, 46%, 0%, and 40% for T1 through T4, respectively. Univariate analysis revealed increased age as a risk factor (P =. 062), and multivariate analysis demonstrated age as a risk factor and performance of neck dissection having a decreased risk of recurrence (P =. 029 and. 023, respectively). Conclusion: We report fairly high disease‐free survival rates in this patient population. Performance of neck dissection and younger age were associated with a favorable prognosis. Performance of neck dissection may decrease the risk of recurrences in primary squamous cell carcinoma of the buccal mucosa.
- Subjects
SQUAMOUS cell carcinoma; ONCOLOGIC surgery; MUCOUS membrane cancer
- Publication
Otolaryngology-Head & Neck Surgery, 2011, Vol 145, pP181
- ISSN
0194-5998
- Publication type
Abstract
- DOI
10.1177/0194599811415823a154