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- Title
Neutrophil–Lymphocyte Ratio and Platelet–Lymphocyte Ratio Combination Can Predict Prognosis in Patients With ST-Segment Elevation Myocardial Infarction Undergoing Primary Percutaneous Coronary Intervention.
- Authors
Çiçek, Gökhan; Açıkgoz, Sadık Kadri; Bozbay, Mehmet; Altay, Servet; Uğur, Murat; Uluganyan, Mahmut; Uyarel, Huseyin
- Abstract
We assessed the effect of combination of neutrophil–lymphocyte ratio (NLR) and platelet–lymphocyte ratio (PLR) in predicting in-hospital and long-term mortality in patients (n = 2518) undergoing primary percutaneous coronary intervention (pPCI). Cutoff values for NLR and PLR were calculated with receiver–operating characteristic (ROC) curves. If both PLR and NLR were above the threshold, patients were classified as “high risk.” If either PLR or NLR was above the threshold individually, patients were classified as “intermediate risk.” High-risk (n = 693) and intermediate-risk (n = 545) groups had higher in-hospital and long-term mortality (7.2 4% vs 0.7%, P < .001; 14.1, 9.5% vs 4.5%, P < .001, respectively). Classifying patients into intermediate-risk group (hazards ratio [HR]: 1.492, 95% confidence interval [CI]: 1.022-2.178, P = .038) and high-risk group (HR: 1.845, 95% CI: 1.313-2.594, P < .001) was an independent predictor of in-hospital and long-term mortality. The combination of PLR and NLR can be useful for the prediction of in-hospital and long-term mortality in patients undergoing pPCI.
- Subjects
MORTALITY risk factors; BLOOD platelets; CARDIOVASCULAR diseases risk factors; CHI-squared test; CONFIDENCE intervals; FISHER exact test; LYMPHOCYTES; MYOCARDIAL infarction; MYOCARDIAL revascularization; NEUTROPHILS; REFERENCE values; T-test (Statistics); TRANSLUMINAL angioplasty; PREDICTIVE tests; RECEIVER operating characteristic curves; DATA analysis software; DESCRIPTIVE statistics; MANN Whitney U Test; PROGNOSIS
- Publication
Angiology, 2015, Vol 66, Issue 5, p441
- ISSN
0003-3197
- Publication type
Article
- DOI
10.1177/0003319714535970