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- Title
B Cell-Adaptive Immune Profile in Emphysema-Predominant Chronic Obstructive Pulmonary Disease.
- Authors
Sullivan, John-Lawrence; Glass, Carolyn; Sholl, Lynette; Kraft, Monica; Bastarrika, Gorka; Estepar, Raul San Jose; Guerra, Stefano; Polverino, Francesca; Bagevalu, Bhavani; Martinez, Fernando D; de-Torres, Juan P; San Jose Estepar, Raul
- Abstract
The article discusses that Global Initiative for Obstructive Lung Disease (GOLD) category of chronic obstructive pulmonary disease (COPD) severity are remarkably heterogeneous. It mentions that computed tomography (CT) has been instrumental in identifying COPD subphenotypes, such as airway disease (AD) and parenchymal destruction; and also mentions that oligoclonal rearrangement of the immunoglobulin genes has been observed in B cells.
- Subjects
OBSTRUCTIVE lung diseases; PULMONARY emphysema; COMPUTED tomography; IMMUNOGLOBULIN genes; B cells; RESEARCH; LUNGS; RESEARCH methodology; EVALUATION research; MEDICAL cooperation; COMPARATIVE studies; IMMUNITY
- Publication
American Journal of Respiratory & Critical Care Medicine, 2019, Vol 200, Issue 11, p1434
- ISSN
1073-449X
- Publication type
letter
- DOI
10.1164/rccm.201903-0632LE