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- Title
Immune checkpoint inhibitors: Navigating a new paradigm of treatment toxicities.
- Authors
Roberts, Kate; Culleton, Vanessa; Lwin, Zarnie; O'Byrne, Kenneth; Hughes, Brett GM
- Abstract
Immune checkpoint inhibitors have recently emerged as an exciting new treatment paradigm across a broad spectrum of malignancies. This new class of agents also challenges oncologists with a unique set of immune-based toxicities. Early recognition and precise management of these toxicities can result in better outcomes, with minimization of toxicity and harm to the patient. This article provides a comprehensive review of immune-based toxicities caused by immune checkpoint inhibitors, including recommendations for their investigation and guidelines for specific management.
- Subjects
CANCER treatment complications; IMMUNOTHERAPY; ONCOLOGISTS; DRUG toxicity; TREATMENT effectiveness
- Publication
Asia Pacific Journal of Clinical Oncology, 2017, Vol 13, Issue 4, p277
- ISSN
1743-7555
- Publication type
Article
- DOI
10.1111/ajco.12698