We found a match
Your institution may have access to this item. Find your institution then sign in to continue.
- Title
Microbial Profile, Antimicrobial Susceptibility, and Prevalence of MDR/XDR Pathogens Causing Medical Device Associated Infections: A Single Center Study.
- Authors
Suryawanshi, Vaibhav R.; Pawar, Atmaram; Purandare, Bharat; Vijayvargiya, Niveda; Sancheti, Sandesh; Philip, Susan; Nagare, Prasad
- Abstract
Background: There is a scarcity of studies evaluating the microbial profile, antimicrobial susceptibility, and prevalence of MDR/XDR pathogens causing medical device-associated infections (MDAIs). The present study was sought in this regard. Materials and methods: An ambispective-observational, site-specific, surveillance-based study was performed for a period of 2 years in the intensive care unit (ICU) and high dependency unit (HDU) (medicine/surgery) of a Tertiary-care University Hospital. Three commonly encountered MDAIs including central-line-associated bloodstream infections (CLABSI), catheter-associated urinary tract infections (CAUTI), and ventilatorassociated pneumonia (VAP), were targeted. Results and conclusion: Of the total 90 patients, 46 (51.1%) were admitted to the ICU (medicine/surgery), and the remaining 44 (48.8%) were admitted to the HDU (medicine/surgery). The median (P25-P75) age of the total patients was 55 (43.1-62.3) years. Male 61 (67.8%) preponderance was observed. Sixty-two of 90 (68.9%) were immunocompromised. A total of 104 pathogens causing MDAIs were isolated. Staphylococcus epidermidis (CoNS), and Staphylococcus capitis were commonly isolated multi-drug resistant (MDR) gram-positive pathogens causing MDAIs. Similarly, carba-resistant Klebsiella pneumoniae, Stenotrophomonas maltophilia, and carba-resistant Acinetobacter baumanni were commonly isolated MDR gram-negative pathogens causing MDAIs. Five of 9 (55.5%) K. pneumoniae and three of 9 (33.3%) S. maltophilia isolates were found to be extensively drug resistant. Among Candida, C. parapsilosis was the most prevalent fungal pathogen causing CLABSI and CAUTI in patients admitted to ICU/HDU.
- Subjects
INDIA; INTENSIVE care units; KLEBSIELLA; SCIENTIFIC observation; CATHETER-related infections; MICROBIOLOGY; PHENOMENOLOGICAL biology; IMMUNOCOMPROMISED patients; CROSS infection; TERTIARY care; CATHETER-associated urinary tract infections; MULTIDRUG resistance; DISEASE prevalence; DESCRIPTIVE statistics; STAPHYLOCOCCUS; PATHOGENIC microorganisms; VENTILATOR-associated pneumonia; GRAM-positive bacteria; BLOODBORNE infections
- Publication
Indian Journal of Critical Care Medicine, 2024, Vol 28, Issue 2, p152
- ISSN
0972-5229
- Publication type
Article
- DOI
10.5005/jp-journals-10071-24623