We found a match
Your institution may have access to this item. Find your institution then sign in to continue.
- Title
Dominance of Three Sublineages of the SARS-CoV-2 Delta Variant in Mexico.
- Authors
Taboada, Blanca; Zárate, Selene; García-López, Rodrigo; Muñoz-Medina, José Esteban; Sanchez-Flores, Alejandro; Herrera-Estrella, Alfredo; Boukadida, Celia; Gómez-Gil, Bruno; Selem Mojica, Nelly; Rosales-Rivera, Mauricio; Salas-Lais, Angel Gustavo; Gutiérrez-Ríos, Rosa María; Loza, Antonio; Rivera-Gutierrez, Xaira; Vazquez-Perez, Joel Armando; Matías-Florentino, Margarita; Pérez-García, Marissa; Ávila-Ríos, Santiago; Hurtado, Juan Manuel; Herrera-Nájera, Carla Ivón
- Abstract
In this study, we analyzed the sequences of SARS-CoV-2 isolates of the Delta variant in Mexico, which has completely replaced other previously circulating variants in the country due to its transmission advantage. Among all the Delta sublineages that were detected, 81.5 % were classified as AY.20, AY.26, and AY.100. According to publicly available data, these only reached a world prevalence of less than 1%, suggesting a possible Mexican origin. The signature mutations of these sublineages are described herein, and phylogenetic analyses and haplotype networks are used to track their spread across the country. Other frequently detected sublineages include AY.3, AY.62, AY.103, and AY.113. Over time, the main sublineages showed different geographical distributions, with AY.20 predominant in Central Mexico, AY.26 in the North, and AY.100 in the Northwest and South/Southeast. This work describes the circulation, from May to November 2021, of the primary sublineages of the Delta variant associated with the third wave of the COVID-19 pandemic in Mexico and highlights the importance of SARS-CoV-2 genomic surveillance for the timely identification of emerging variants that may impact public health.
- Subjects
MEXICO; SARS-CoV-2 Delta variant; SARS-CoV-2; PUBLIC health surveillance; COVID-19 pandemic; SOCIAL dominance; COVID-19
- Publication
Viruses (1999-4915), 2022, Vol 14, Issue 6, pN.PAG
- ISSN
1999-4915
- Publication type
Article
- DOI
10.3390/v14061165