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- Title
The threshold for diagnosing impaired fasting glucose: a position statement by the European Diabetes Epidemiology Group.
- Authors
Forouhi, N. G.; Balkau, B.; Borch-Johnsen, K.; Dekker, J.; Glumer, C.; Qiao, Q.; Spijkerman, A.; Stolk, R.; Tabac, A.; Wareham, N. J.
- Abstract
The category of IFG was introduced in the late 1990s to denote a state of non-diabetic hyperglycaemia defined by a fasting plasma glucose (FPG) concentration between 6.1 and 6.9 mmol/l. In 2003 the American Diabetes Association recommended that this diagnostic threshold be lowered to 5.6 mmol/l. The justification for lowering the threshold has been questioned. This simple change in cut-off value creates a pandemic of IFG, with a two- to five-fold increase in the prevalence of IFG across the world. Such a change in threshold has far-reaching public health implications. The European Diabetes Epidemiology Group (EDEG) has reviewed the evidence for this lower cut-off point for the definition of IFG and concludes that the previous definition should not be altered. EDEG further recommends that the value of all categorical definitions of non-diabetic hyperglycaemia should be reconsidered.
- Subjects
GLUCOSE; DIAGNOSIS; HYPERGLYCEMIA; DIABETES; AMERICAN Diabetes Association; EPIDEMIOLOGY
- Publication
Diabetologia, 2006, Vol 49, Issue 5, p822
- ISSN
0012-186X
- Publication type
Article
- DOI
10.1007/s00125-006-0189-4